This research letter is a retrospective analysis of Medicare and private insurance claims (2017–2024) which found that nurse anesthetists’ share of interventional pain management procedures, especially facet joint/medial branch blocks and radiofrequency ablations, roughly doubled over the study period, though they still perform a small overall fraction of such procedures. The authors note this growth, concentrated in lumbar/sacral and non-image-guided procedures, may accelerate given rising nurse anesthetist employment and declining pain medicine fellowship applications, and they call for comparative outcome studies akin to those done for operating-room anesthesia care.