I am an Infectious Diseases physician scientist focused on the overlapping epidemics (syndemic) of substance use disorders and infectious diseases. I am also an HIV and HCV provider at Boston Medical Center and the Boston Healthcare for the Homeless Program, where I provide primary care and sub-specialty management of HIV, HCV, and HIV/HCV co-infected patients, most of whom have opioid use disorder. My research investigates the comparative- and cost-effectiveness of interventions to identify and treat OUD, HIV, HCV, and serious injection-related bacterial infections in the real world, where resources are limited and the best strategies for obtaining good outcomes are not certain.