Improving Pain Management and Opioid Safety Through a Systemwide Data-Driven Evaluation of the CDC Opioid Prescribing Guideline Best Practices and the Use of Clinical Decision Support


Jason Hoppe

Prime Institution: University of Colorado

Effectively treating pain while safely prescribing opioid pain medication to prevent opioid use disorder and overdose is a public health priority. Clinical decision support (CDS) is a promising strategy to operationalize evidence-based practices in pain management and maximize the value of routinely collected data. The investigators will use electronic health record-embedded CDS to modify provider behavior toward CDC guideline-concordant recommendations. This project will foster a data-driven learning health system by linking Prescription Drug Monitoring Program, insurance claims, and death data to evaluate patient outcomes. A hybrid effectiveness-implementation trial in a health system will evaluate the association between CDC guideline-concordant actions and patient outcomes and assess the effectiveness of a CDS to facilitate evidence-based pain management approaches in comparison to usual care. Results will document the effectiveness of CDC guideline-concordant prescribing and a scalable implementation strategy using existing data to decrease morbidity and mortality from the opioid crisis.

Hoppe - Heather Tolle

Jason Hoppe, MD, University of Colorado, PD/PI

Dr. Jason Hoppe is a clinician-researcher, medical toxicologist, and Associate Professor of Emergency Medicine at the University of Colorado School of Medicine. His clinical work, research, and public health efforts are aimed at addressing the complicated decision-making process regarding the safe prescribing of opioid analgesics and effectively initiating treatment for patients with an opioid use disorder. He is a national expert in prescription opioid safety, prescription drug monitoring programs (PDMP), and ED buprenorphine use. He is interested in using clinical decision support as an implementation strategy to deliver evidence-based practices. Dr. Hoppe is a founding member of the Colorado Consortium for Prescription Drug Abuse Prevention and has assisted with multiple public health efforts, education programs, and successful legislative changes in Colorado regarding PDMP access, opioid prescribing, and medications for opioid use disorder.